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Farm Comunitarios. 2020 Oct 13;12(4):5-20. doi: 10.33620/FC.2173-9218.(2020/Vol12).004.02

The ‘ADHIFAC’ study protocol: assessment of adherence to glucose lowering medication and detection of hypoglycemia in Spanish community pharmacies

Ruiz D1, 2, Fornos Pérez JA3, 4, Gómez-Peralta F5, Molinero A3, 6, Sánchez Barrancos IM7, Arranz Martínez E8, Mera Gallego I3, 9, Andrés-Rodríguez NF1, 10
1. Grupo de Diabetes de la Sociedad Española de Farmacia Familiar y Comunitaria (SEFAC). 2. Farmacéutica comunitaria en Valencia. 3. Grupo de Diabetes de la Sociedad Española de Farmacia Familiar y Comunitaria (SEFAC). 4. Farmacéutico comunitario en Cangas de Morrazo (Pontevedra). 5. Especialista en Endocrinología. Sociedad Española de Diabetes (SED). 6. Farmacéutica comunitaria en Fuenlabrada (Madrid). 7. Médico. Grupo de Diabetes de la Sociedad Española de Medicina de Familia y Comunitaria (semFYC). 8. Médico. Grupo de Diabetes de la Sociedad Española de Médicos de Atención Primaria (SEMERGEN). 9. Farmacéutica comunitaria en Maella (Zaragoza). 10. Farmacéutico comunitario en Vigo (Pontevedra).
Ruiz D, Fornos JA, Gómez-Peralta F, Molinero A, Sánchez IM, Arranz E, Mera I, Andrés-Rodríguez NF. The ‘ADHIFAC’ study protocol: assessment of adherence to glucose lowering medication and detection of hypoglycemia in Spanish community pharmacies. Farm Comunitarios. 2020 Oct 13;12(4):5-20. doi: 10.33620/FC.2173-9218.(2020/Vol12).004.02
Abstract : 

Introduction: Lack of adherence results in worse control of diabetes and an increased number of complications, often resulting in higher healthcare spending. Hypoglycemia, which is sometimes unrecognized, is one of the main consequences of non-adherence to treatment. It is prevented through multidisciplinary interventions which help improve adherence.

Objectives: to measure adherence to hypoglycemic agents, to detect and quantify unrecognized and recurrent hypoglycemia, to learn patients’ perceptions of their treatment and refer them to physicians in cases of non-adherence and unsolved hypoglycemia.

Material and methods: an observational, cross-sectional, multicenter study in community pharmacies, conducted from April 2019 with type 2 diabetics in treatment with hypoglycemic agents for ³12 months on the same drug regimen. To detect hypoglycemia, those treated with sulfonylureas, glinides and/or insulin.

Design of a questionnaire with sociodemographic data, diseases and treatments.

Use of the MMAS-8 test for non-adherence and the Clarke hypoglycemia awareness test.

If non-compliance and/or hypoglycemia is detected and cannot be resolved by the pharmacist, it will be referred to the family physician.

Statistical analysis: the STATA13 program will be used for Windows®. Bivariate and multivariate analyses will be conducted. Statistical significance will be set at p<0.05.

Applicability of the results: we hope to gain awareness of the lack of adherence and its causal factors and the prevalence of unrecognized hypoglycemia so that, in another project, an efficient pharmaceutical intervention program can be established to improve adherence to pharmacotherapy of patients treated with hypoglycemic agents and reduce the occurrence of hypoglycemia.

 

 

 

 

 

 

 

 

 

 

 

 

 

Keywords : 
Diabetes Mellitus, Type 2; medication adherence; hypoglycemia; Community Pharmacy Services; physicians
Article download link: 
PDF icon fc2020-12-4-02adhifac-eng.pdf

Editor: © SEFAC. Sociedad Española de Farmacia Clínica, Familiar y Comunitaria. 
Copyright© SEFAC. Sociedad Española de Farmacia Clínica, Familiar y Comunitaria. This article is available from url https://www.farmaceuticoscomunitarios.org/. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit https://creativecommons.org/licenses/by-nc-nd/4.0/

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